I had this same issue after starting my computer about 4 months of it sitting still. I had to update iCue and noticed my mic wouldn't come off of mute, only "mic feedback on/off". Well after 3 days of nonstop attempts, I did something a little simple that fixed it.
Unplug your USB headphones.
Close iCUE.
Go to your Control Panel.
Click on Programs.
Click on Uninstall a Program.
Right click on CORSAIR iCUE Software.
Click Repair.
Follow onscreen instructions.
Plug headset back in.
This worked for me out of all the tedious things I tried, hopefully this solves everyone else's issue :)