Holy crap this is awesome. THANK YOU. I never imagined Mystic Light will overwrite (let alone work with) iCUE. Can't imagine how many times I tried deleting profiles on iCUE and even hard resetting my M65 elite only to realize it was Dragon Center running the show.
Although in my case even though I disabled the overwrite setting on Dragon Center it was still Mystic Light controlling the mouse RGB. I think I had to delete the mouse RGB profile on Dragon Center then redo the hardware light settings on iCUE.