Don't worry, have the same problem.
Build:
ASUS ROG STRIX B450-F GAMING (last bios)
AMD Ryzen 2600X
have CMW16GX4M2C3200C16 x4
tested x2 in dual channel to XMP to 3200Mhz work fine, bt if put x4 modules, system fail and instareset, back to default 2133 Mhz
now im working with gskill rgb 2400@2800Mhz x4 without problem.