Took some messing around, but I managed to get it to work.
For the sake of safety I did a number of things, as such, I recommend doing them all.
>Make sure icue and your mouse is up to date
>Completely close the program (right click icon in bottom right and click quit)
>Repair program installation
>Make sure your mouse, if wireless, is plugged in. It has to actually 'upload' the macros.
This is how I got it to work. Best of luck.