I don't know if my issue is the same, but I have the m65 rgb mouse, second one I've owned and same issue
While playing overwatch, my aim reticle will suddenly jerk straight down or up. But it only does it for that split second.
Out of curiosity I just saved my lighting and dpi profiles to my mouse, and closed corsair utility engine. I didn't experience any issue last night, but it happens so randomly that it's too early to tell that there's something wrong with CUE.