I have the same problem. iCue crashes on startup. I have also tried the instructions to completely remove and reinstall. I DO NOT have and Asus motherboard (or anything Asus). It used to work perfectly before today. The only change is a network card. (Had to go fiber.) CatX no longer available.
K100
Dark Core Pro SE
MM1000
Virtuoso Pro
iCue Nexus
Vengeance Pro RGB 3600
6x LL120 Fans