So I've come here looking for a solution to the same problem.
as a relatively new member of the RGB community, I feel like it took me long enough to find which ecosystem to adopt. eventually decided to settle on iCUE because of some of the benefits that it offered. I also happen to have Corsair RAM which helped make the decision.
Now that I'm using iCUE I'm having the same issues.
My fix is at least easy enough. I just need to open and make active the iCUE window and profiles apply, but it's still frustrating. iCUE is running in the background, it should work.
Is it supposed to write the preferred profile to the hardware? Like in some non-volatile memory somewhere? My ASUS motherboard and my Wraith Prism can do it just fine.
Some reading here and here has shown that Corsair has known about this issue since mid-2018, and the problem has apparently been on their "fix-list" since then.
It's sad that we're still waiting for what should be a quick fix.
Think maybe he meant changed the registry reference? I might try this myself and advise.
