I had just had this problem today. I tried or was going to try the thing Metazolid tried then noticed I didn't have whatever an Hsmgr is and as I was sitting here it occurred to me that the last time I ever ran into a file error problem was when I had gotten my windows vista and had installed the first sims game on it. It wasn't letting me play it because of a file something error (Don't remember exactly what it was called it had been ages ago.) I thought let me do the same thing. This is what I did step by step.
I right clicked on the iCUE icon on my desktop.
I clicked properties.
I clicked comparability
I scrolled to what windows I needed it to be compatible with and checked the box then hit apply.
and as a test I restarted my computer and it works just fine. Started up fine and no more annoying error thing.