Hi! Having the issue, same thing in logs everyone else sees (nothing I can find but those pages and pages of "request timed out" messages). I note: The mouse buttons DO work when this is happening. They're just really, really, slow. It can take about a second of pressing before the press registers, and a release can also take quite a while to register.
Set to 500Hz, and it did happen after a while, but I believe it took significantly longer. I'm now at 250Hz and will see what that does. I'm expecting it to take even longer at that point, but I bet it'd still happen if I left things up for a day or so.
Note: Can't change settings when the mouse is doing this, because any attempt to change something like polling settings causes the mouse to eventually crash, disconnect, and reconnect as a generic HID device. (Although I think the settings may actually make it to the mouse, for when it next comes up.) When that happens, CUE crashes also, but if I restart cue, it comes up fine... but doesn't see the mouse.
CUE 1.12.75, mouse is 1.06/0.02 firmware/bootloader. Problem has existed as long as I've had mouse, never had different software versions.
Side note: You know what would be super convenient? A quick way to assign keys on the mouse to "the next key I hit", or just a "set thumb buttons to numeric keypad" button.
Also, although this applies more to things like the keyboard, it might be handy to have a way to apply something like a gradient effect to a range of keys. So, doing the gradient over space, not time. (So, say, you make a rainbow gradient, then apply it to "all the keys", and then they just have static lighting that's a smooth gradient, instead of having to manually adjust colors of keys.)