@Corsair Nick, the Firmware versions I was having huge problems with was:
Dongle - 1.7.58
Mouse - 1.9.85
I reverted to these older versions at the end of Feb and have had little or no problems since:
Dongle - 0.5.49
Mouse - 0.5.64
To confirm, this was not limited to any specific application but generally would action multiple clicks on one mouse button press regardless of what or where you were clicking - desktop icons, Excel, games etc. etc.
For the record, the trick of reverting to an older iCue did not work for me, only the rollback of firmware.
There have been updates to iCue since but I have not dared to try the latest firmware's (if there are any!) purely to save myself the hassle as the old ones appear to be working.