I noticed that when I launch Diablo 3, my K68 RGB uses the native lighting settings and I can't get it to use the profile I made for it instead. My Glaive still uses my custom profile, but not my keyboard.
With my Razer peripherals, there's an option to use the native game lighting "preset" profile or my own custom profile; is there an option to do this in iCUE that I'm somehow missing?