SixPoint

I'm trying to build a liquid cooled Pc, and i guess I'm being picky. I want to use all the same product for fans and rgb lighting. Problem is i hate missing areas. My case that I'm ordering supports 13 fans, and i would like to use rgb fans in at least 12, then i have the CPU water block, and gpu and accent lighting as well. My question is, can i run 2 commander pros and plug them into different usb ports on the motherboard?