Man it looks like your issues started the same day as mine. I got the mouse in September and my issues started Thurs Dec. 5, 2019.
Same as what everyone above has mentioned. DPI settings changed and the profiles too in the middle of a game even though the profile is set to start up with the game.
Then after the new version of iCue came out I uninstalled 2. Whatever it was and cleared the registry, and removed every single iCue related folder from my computer before installing the updated 3.23 version. This time though, the hardwired profiles don't appear at all and my profile settings keep changing on their own still. And of course I have to unplug and reinsert the dongle, or unplug and plug the mouse back in. Soft resets do nothing, can't hard reset without a firmware download that Corsair is supposed to provide, but I submitted a ticket 5 days ago and no response yet.