Macros no working after lastest update?

I have a Darcore RGB.

Nothing has changed on my system accept the latest firmware and software updates for this mouse. Everything worked fine before hand, afterwards macros do not work at all. Profiles switch, normal three buttons work, but assigned macros will not fire off. Not just in one game, they are not working with any program.

Removing and reinstalling iCue, same results.

Any ideas on what might be the issue?