I was hoping the recent iCue software update would fix this, however the issue remains and is totally random. If I am about to speak to someone in Discord, Steam chat or Teamspeak it is a roll of the dice whether the microphone works.
Sometimes it will work from the start of a conversation or game, then if there is some moments of quiet the mic suddenly stops working.
My workaround at this point is to go to my new "Set up Microphone" desktop shortcut, (handy now that the mic stops so often) and run the Headset Microphone wizard to get it working again.