Had a couple days of relatively light issues with 3.25.60, crashes in background that seemingly recover without me even noticing and dashboard inaccuracies. This morning however, after ICUE crashed on boot, it refused to start whatsoever. After rebooting it continued to crash, tried a shutdown and flipping the PSU switch off for a bit and still crashing.
Had to just go in and uninstall, twice actually, first time I didn't check the box to delete data for all users and it continued to crash after reinstall.
Went back to 3.17.94, so far so good. If you haven't updated to 3.25.60, just don't.
edit: Solid day of gaming with no issues from ICUE when using 3.17.94. Definitely going to be hesitant about updates from here out...